Cryo lift-out
Cryo lift-out
Cryo lift-out

Cryo lift-out

Performing in situ cryo TEM sample liftouts of site specific TEM slices prepared in cryo FIBs is in increasing demand.

Relying on our experience in manufacturing microgrippers for standard TEM sample preparation, we've designed a cryo-compatible version of the microgrippers that can be cooled to LN2 temperatures.

The gripper is mounted to an MM3A-EM that has been enhanced for use with the cryo gripper using an insulated holder. The insulation allows the micromanipulator to remain at room temperature while the gripper is cooled by connecting it to the microscope's cryo-system.

Unique solution for cryo TEM sample preparation

  • Simple, gentle grip for retrieving samples
  • No need for water vapour injection
  • Interfacing solutions for most microscopes and cryo systems
  • Fast setup and removal

Clear and simple

  • Result-oriented operation and increased throughput
  • Intuitive control software
  • User-friendly and easy to learn
  • Compact, stand-alone electronics with PC interface

Robust and stable

  • Compact construction delivers higher resonance frequencies
  • Excellent stability
  • Low drift (1 nm/min)
  • Reliable operation (one year endurance test)
  • Virtually insusceptible to vibrations

Fast and precise

  • No backlash or reversal play
  • Sub-nanometer resolution (0.25 nm)
  • No "blind axis" like with cartesian systems
  • Integrated coarse and fine displacement in one drive

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Frequently asked questions about Cryo lift-out